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Coeliac disease Content Supplied by NHS Choices
Introduction

Coeliac disease is a common digestive condition where a person has an adverse reaction to gluten.

Eating foods containing gluten can trigger a range of symptoms, such as:

  • diarrhoea - which may be particularly unpleasant smelling
  • bloating and flatulence (passing wind)
  • abdominal pain
  • weight loss
  • feeling tired all the time - as a result of not getting enough nutrients from food (malnutrition)
  • children not growing at the expected rate

Symptoms can range from mild to severe.

Read more about the symptoms of coeliac disease.

What causes coeliac disease?

Coeliac disease is what is known as an autoimmune condition. This is where the immune system - the body's defence against infection - mistakenly attacks healthy tissue.

Coeliac disease isn't an allergy or an intolerance to gluten.

In cases of coeliac disease the immune system mistakes substances found inside gluten as a threat to the body and attacks them.

This damages the surface of the small bowel (intestines), disrupting the body's ability to absorb nutrients from food.

Exactly what causes the immune system to act in this way is still not entirely clear although a combination of a person's genetic make-up and the environment appear to play a part.

Read more about the causes of coeliac disease.

Gluten

Gluten is a protein found in three types of cereal:

  • wheat
  • barley
  • rye

Gluten is found in any food that contains the above cereals including:

  • pasta
  • cakes
  • breakfast cereals
  • most types of bread
  • certain types of sauces
  • some types of ready meals

In addition most beers are made from barley.

Treating coeliac disease

There is no cure for coeliac disease, but switching to a gluten-free diet should help control symptoms and prevent long term consequences of the disease.

Even if symptoms are mild or non-existent it is still recommended to change your diet as continuing to eat gluten can lead to serious complications (see below).

It is important to make sure your gluten-free diet is healthy and balanced. An increase in the range of available gluten-free foods in recent years has made it possible to eat both a healthy and varied gluten-free diet.

Read more about the treatment of coeliac disease.

Screening

Currently, screening for coeliac disease is not routinely carried out in England.

It is usually only recommended for people at an increased risk of developing the condition, such as having a family history of the disease. It is recommended that first degree relatives (parents,brothers, sisters and children) of people with coeliac disease are screened.

See diagnosing coeliac disease for more information about who should be screened for coeliac disease.

Complications

Complications of coeliac disease tend to only affect people who continue to eat gluten or who have yet to be diagnosed with the condition (which can be a common problem in milder cases.)

Potential long-term complications include:

  • osteoporosis (weakening of the bones)
  • anaemia - lack of red blood cells which can cause breathlessness, tiredness and lack of energy

Less common and more serious complications include those affecting pregnancy, such as low birth weight, and some types of cancers, such as bowel cancer.

Read more about the complications of coeliac disease.

Who is affected

Coeliac disease is a common condition that affects approximately 1 in every 100 people in the UK. However, some experts think this may be an underestimate as milder cases may go undiagnosed or misdiagnosed as other digestive conditions, such as irritable bowel syndrome (IBS).

Reported cases of coeliac disease are two to three times higher in women than men and can develop at any age, although symptoms are most likely to first develop:

  • during early childhood between the ages of 8-12 months (though it may take several years before a correct diagnosis is made), or 
  • in later adulthood between the ages of 40 to 60 years
 
 
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